{"id":2570,"date":"2021-03-01T06:00:31","date_gmt":"2021-02-28T21:00:31","guid":{"rendered":"http:\/\/www.emukk.com\/WP\/?p=2570"},"modified":"2021-07-21T23:31:31","modified_gmt":"2021-07-21T14:31:31","slug":"%e4%bb%8a%e6%9b%b4%e3%81%a7%e3%81%99%e3%81%8c%e3%80%81c-type-lectin-cd209-dc-sign-cd209l-l-sign%e3%81%8c%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88sars","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e4%bb%8a%e6%9b%b4%e3%81%a7%e3%81%99%e3%81%8c%e3%80%81c-type-lectin-cd209-dc-sign-cd209l-l-sign%e3%81%8c%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88sars\/","title":{"rendered":"\u4eca\u66f4\u3067\u3059\u304c\u3001C\u578b\u30ec\u30af\u30c1\u30f3 CD209\/DC-SIGN, CD209L\/L-SIGN\u304c\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u306e\u611f\u67d3\u53d7\u5bb9\u4f53\u306b\u306a\u308a\u5f97\u308b\u3068\u3044\u3046\u6307\u6458"},"content":{"rendered":"<p>\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u306e\u611f\u67d3\u53d7\u5bb9\u4f53\u306f\u3001ACE2\u4ee5\u5916\u306b\u3001C\u578b\u30ec\u30af\u30c1\u30f3\u3082\u305d\u3046\u3067\u3042\u308b\u3001\u3068\u3044\u3046\u6307\u6458\u306f\u4e0b\u8a18\u306e\u8ad6\u6587\u306b\u898b\u308b\u3053\u3068\u304c\u51fa\u6765\u307e\u3059\u3002<br \/>\nHarvard Medical School, July 30, 2020<br \/>\n<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2020.07.29.227462v1\">https:\/\/www.biorxiv.org\/content\/10.1101\/2020.07.29.227462v1<\/a><br \/>\nBoston University, Dec. 9, 2020<br \/>\n<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2020.06.22.165803v2\">https:\/\/www.biorxiv.org\/content\/10.1101\/2020.06.22.165803v2<\/a><br \/>\nBoston University, (Dec. 22, 2020)\u3088\u308aReview\u3068\u3044\u3046\u5f62\u3067\u306e\u8ad6\u6587\u304c\u3042\u308a\u307e\u3057\u305f\u306e\u3067\u3001\u305d\u308c\u3092\u53c2\u8003\u306b\u3075\u305f\u3064\u306e\u30c7\u30fc\u30bf\u3092\u7d39\u4ecb\u3057\u3088\u3046\u3068\u601d\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.mdpi.com\/2079-7737\/10\/1\/1\">https:\/\/www.mdpi.com\/2079-7737\/10\/1\/1<\/a><\/p>\n<p>ACE2\u306f\u78ba\u304b\u306b\u4e3b\u8981\u306a\u611f\u67d3\u53d7\u5bb9\u4f53\u3067\u306f\u3042\u308b\u306e\u3067\u3059\u304c\u3001\u80ba\u3067\u306f\u305d\u308c\u307b\u3069\u767a\u73fe\u91cf\u304c\u9ad8\u304f\u306a\u304f\u3001\u3080\u3057\u308dCD209\/DC-SIGN\u306e\u65b9\u304c\u767a\u73fe\u91cf\u304c\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002<br \/>\nCD209L, CD209, ACE2\u3092\u904e\u5270\u767a\u73fe\u3055\u305b\u305fHEK293\u7d30\u80de\u3092\u7528\u3044\u3066\u3001SARS-CoV-2\u306e\u7591\u4f3c\u30a6\u30a4\u30eb\u30b9\u3092\u611f\u67d3\u3055\u305b\u305f\u5b9f\u9a13\u3082\u4e0b\u8a18\u306b\u793a\u3057\u307e\u3059\u3002<br \/>\nACE2\u306f\u611f\u67d3\u53d7\u5bb9\u4f53\u3068\u3057\u3066\u4e00\u7fa9\u7684\u306b\u91cd\u8981\u306a\u306e\u3067\u3059\u304c\u3001ACE2\u306e\u767a\u73fe\u304c\u5f31\u3044\u7d44\u7e54\u3067\u306f\u3001C\u578b\u30ec\u30af\u30c1\u30f3\u304cSARS-CoV-2\u306e\u611f\u67d3\u3092\u5927\u3044\u306b\u4ecb\u5728\u3057\u3066\u3044\u308b\u3053\u3068\u306f\u4e8b\u5b9f\u3067\u3057\u3087\u3046\u3002<br \/>\n\u306a\u304a\u3001\u3053\u308c\u3089C-type Lectin\uff08DC-SIGN, L-SIGN\uff09\u306eCRD\u306f\u3001High Mannose\u69cb\u9020\u3092\u5f37\u304f\u8a8d\u8b58\u3057\u307e\u3059\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/02\/CD209ACE2-expressions.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-large wp-image-2571\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/02\/CD209ACE2-expressions-1024x195.png\" alt=\"\" width=\"696\" height=\"133\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/02\/CD209ACE2-expressions-1024x195.png 1024w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/02\/CD209ACE2-expressions-600x114.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/02\/CD209ACE2-expressions-300x57.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/02\/CD209ACE2-expressions-768x146.png 768w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/02\/CD209ACE2-expressions-1536x292.png 1536w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/02\/CD209ACE2-expressions.png 1795w\" sizes=\"auto, (max-width: 696px) 100vw, 696px\" \/><\/a><\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/02\/CD209_CD209L.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-2572\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/02\/CD209_CD209L-184x300.png\" alt=\"\" width=\"184\" height=\"300\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/02\/CD209_CD209L-184x300.png 184w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2021\/02\/CD209_CD209L.png 358w\" sizes=\"auto, (max-width: 184px) 100vw, 184px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u306e\u611f\u67d3\u53d7\u5bb9\u4f53\u306f\u3001ACE2\u4ee5\u5916\u306b\u3001C\u578b\u30ec\u30af\u30c1\u30f3\u3082\u305d\u3046\u3067\u3042\u308b\u3001\u3068\u3044\u3046\u6307\u6458\u306f\u4e0b\u8a18\u306e\u8ad6\u6587\u306b\u898b\u308b\u3053\u3068\u304c\u51fa\u6765\u307e\u3059\u3002 Harvard Medical School, July 30, 2020<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/%e4%bb%8a%e6%9b%b4%e3%81%a7%e3%81%99%e3%81%8c%e3%80%81c-type-lectin-cd209-dc-sign-cd209l-l-sign%e3%81%8c%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88sars\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-2570","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/2570","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=2570"}],"version-history":[{"count":11,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/2570\/revisions"}],"predecessor-version":[{"id":5137,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/2570\/revisions\/5137"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=2570"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=2570"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=2570"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}