{"id":2106,"date":"2021-02-04T11:34:31","date_gmt":"2021-02-04T02:34:31","guid":{"rendered":"http:\/\/www.emukk.com\/WP\/?p=2106"},"modified":"2021-07-21T23:37:44","modified_gmt":"2021-07-21T14:37:44","slug":"%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%e5%9b%9e%e5%be%a9%e6%82%a3%e8%80%85%e3%81%ae%e8%a1%80%e6%bc%bf%e4%b8%ad%e5%92%8c%e6%8a%97%e4%bd%93%e3%81%8c%e5%8a%b9","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%e5%9b%9e%e5%be%a9%e6%82%a3%e8%80%85%e3%81%ae%e8%a1%80%e6%bc%bf%e4%b8%ad%e5%92%8c%e6%8a%97%e4%bd%93%e3%81%8c%e5%8a%b9\/","title":{"rendered":"\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08COVID-19\uff09\u56de\u5fa9\u60a3\u8005\u306e\u8840\u6f3f\u4e2d\u548c\u6297\u4f53\u304c\u52b9\u304b\u306a\u304f\u306a\u308b"},"content":{"rendered":"

\u30ef\u30af\u30c1\u30f3\u958b\u767a\u306e\u91cd\u8981\u306a\u554f\u984c\u306f\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3092\u53d7\u3051\u305f\u4eba\u3005\u306e\u30dd\u30ea\u30af\u30ed\u30fc\u30ca\u30eb\u514d\u75ab\u5fdc\u7b54\u306e\u9078\u629e\u5727\u4e0b\u3067\u3001\u30a6\u30a4\u30eb\u30b9\u304c\u305d\u306e\u514d\u75ab\u304b\u3089\u9003\u308c\u308b\u305f\u3081\u306b\u9032\u5316\u3057\u3066\u3057\u307e\u308f\u306a\u3044\u304b\uff1f\u3068\u3044\u3046\u3053\u3068\u3067\u3042\u308a\u3001\u5909\u7570\u3092\u53d7\u3051\u305f\u30a6\u30a4\u30eb\u30b9\u306b\u5bfe\u3057\u3066\u6709\u52b9\u6027\u3092\u62c5\u4fdd\u3067\u304d\u308b\u304b\uff1f\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n

Fondazione Toscana Life Sciences, Siena, Italy\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08COVID-19\uff09\u56de\u5fa9\u60a3\u8005\u306e\u8840\u6f3f\u4e2d\u304b\u3089\u5f97\u3089\u308c\u305f\u4e2d\u548c\u6297\u4f53\uff08\u30dd\u30ea\u30af\u30ed\u30ca\u30fc\u30eb\uff09\u3092\u7528\u3044\u3066\u3001\u30a6\u30a4\u30eb\u30b9\u3068\u5171\u57f9\u990a\u3092\u884c\u3063\u305f\u7d50\u679c\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002
\nhttps:\/\/pubmed.ncbi.nlm.nih.gov\/33398278\/<\/a><\/p>\n

\u672c\u5b9f\u9a13\u306b\u304a\u3044\u3066\u306f\u300120\u4eba\u306e\u56de\u5fa9\u60a3\u8005\u306e\u4e2d\u548c\u6297\u4f53\u306b\u3064\u3044\u3066\u6700\u3082\u529b\u4fa1\u306e\u9ad8\u3044\u60a3\u8005\u306e\u305d\u308c\u3092\u4f7f\u7528\u3057\u3001VERO E6\u7d30\u80de\u3068SARS-CoV-2\u3092100\u65e5\u9593\uff0814\u7d99\u4ee3\u4ee5\u4e0a\uff09\u306b\u6e21\u3063\u3066\u5171\u57f9\u990a\u3057\u3001\u4e2d\u548c\u6297\u4f53\u306e\u529b\u4fa1\u306e\u5909\u5316\u3068\u30a6\u30a4\u30eb\u30b9\u306b\u767a\u751f\u3057\u305f\u907a\u4f1d\u5b50\u5909\u7570\u306e\u95a2\u4fc2\u3092\u8abf\u67fb\u3057\u3066\u3044\u307e\u3059\u3002\u672c\u5b9f\u9a13\u3067\u306f\u3001S\u30bf\u30f3\u30d1\u30af\u8cea\u306eNTD\u3068RBD\u306b\u4e0b\u8a18\u306e\u3088\u3046\u306a\u5909\u7570\u304c\u8d77\u3053\u3063\u3066\u304a\u308a\u3001\u305d\u308c\u3068\u3068\u3082\u306b\u3001\u4e2d\u548c\u6297\u4f53\u306e\u529b\u4fa1\u304c\u4e0b\u304c\u3063\u3066\u3044\u304f\u69d8\u5b50\u304c\u5982\u5b9f\u306b\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

    \n
  1. deletion of the phenylalanine in position 140 (F140) on the S-protein NTD N3 loop.<\/li>\n
  2. glutamic acid in position 484 of the RBD was substituted with a lysine (E484K).<\/li>\n
  3. 11-amino-acid insertion between Y248 and L249 in the NTD N5 loop (248aKTRNKSTSRRE248k).<\/li>\n<\/ol>\n

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    \"\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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