{"id":2079,"date":"2021-02-03T10:44:01","date_gmt":"2021-02-03T01:44:01","guid":{"rendered":"http:\/\/www.emukk.com\/WP\/?p=2079"},"modified":"2021-07-21T23:38:02","modified_gmt":"2021-07-21T14:38:02","slug":"mannose-binding-lectin-mbl%ef%bc%89%e3%81%ae%e9%81%ba%e4%bc%9d%e5%ad%90%e5%a4%89%e7%95%b0%e3%81%8c%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88covid-19","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/mannose-binding-lectin-mbl%ef%bc%89%e3%81%ae%e9%81%ba%e4%bc%9d%e5%ad%90%e5%a4%89%e7%95%b0%e3%81%8c%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88covid-19\/","title":{"rendered":"Mannose Binding Lectin (MBL\uff09\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08COVID-19\uff09\u306e\u91cd\u75c7\u5ea6\u306b\u5927\u304d\u304f\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3089\u3057\u3044"},"content":{"rendered":"

\u81ea\u7136\u514d\u75ab\u306b\u306f\u3001(1)\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u3084NK\u7d30\u80de\u7b49\u306e\u8caa\u98df\u7d30\u80de\u304c\u4e2d\u5fc3\u3068\u306a\u308b\u8caa\u98df\u3001(2)\u88dc\u4f53\u30ec\u30af\u30c1\u30f3\u7d4c\u8def\u3001(3)\u597d\u4e2d\u7403\u7d30\u80de\u5916\u30c8\u30e9\u30c3\u30d7\u304c\u3042\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u88dc\u4f53\u30ec\u30af\u30c1\u30f3\u7d4c\u8def\u306b\u304a\u3044\u3066\u306f\u3001Mannose Binding Lectin (MBL\uff09\u304c\u4e2d\u5fc3\u7684\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3001\u75c5\u539f\u4f53\u306e\u7d30\u80de\u58c1\u306e\u30de\u30f3\u30ce\u30fc\u30b9\u306bMBL\u304c\u7d50\u5408\u3059\u308b\u3068\u3001MBL\u3068\u7d50\u5408\u3057\u305fMBL\u7d50\u5408\u30bb\u30ea\u30f3\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc(MASP)\u3068\u3044\u3046\u9175\u7d20\u304c\u6d3b\u6027\u5316\u3055\u308c\u3001MASP\u304c\u88dc\u4f53\u7b2c4\u56e0\u5b50(C4)\u3092\u6d3b\u6027\u5316\u3057\u3001\u9806\u6b21\u88dc\u4f53\u3092\u6d3b\u6027\u5316\u3057\u3066\u3001\u6700\u7d42\u7684\u306b\u3001\u75c5\u539f\u4f53\u306e\u7d30\u80de\u58c1\u306b\u7a74\u3092\u3042\u3051\u3066\u6bba\u50b7\u3057\u307e\u3059\u3002<\/p>\n

Istanbul Faculty of Medicine, Istanbul Univ.\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u3053\u306eMBL\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08COVID-19\uff09\u306e\u91cd\u75c7\u5316\u306b\u5927\u304d\u304f\u4fc2\u308f\u3063\u3066\u3044\u308b\u3053\u3068\u3092\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002
\nhttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7838598\/<\/a><\/p>\n

MBL2\u907a\u4f1d\u5b50\u306ecodon52\u306e\u5909\u7570\u306b\u3064\u3044\u3066\u3001
\nAA genotype\u3092\u53c2\u7167\u3068\u3057\u3066\u3001
\nBB genotype: odds ratio (OR)\u202f=\u202f5.3, p\u202f<\u202f0.001;
\nAB genotype: OR\u202f=\u202f2.9, p\u202f=\u202f0.001<\/p>\n

ICU\u306e\u5fc5\u8981\u6027\u306b\u3064\u3044\u3066\u306f\u3001\u66f4\u306bodds\u6bd4\u304c\u5927\u304d\u304f\u306a\u308a
\nBB genotype: OR\u202f=\u202f19.6, p\u202f<\u202f0.001
\nAB genotype: OR\u202f=\u202f6.9, p\u202f=\u202f0.001<\/p>\n

MBL\u3092\u6cbb\u7642\u85ac\u3068\u3057\u3066\u4f7f\u7528\u3059\u308b\u5834\u5408\u306e\u53c2\u8003\u306b\u306a\u308a\u305d\u3046\u3067\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u81ea\u7136\u514d\u75ab\u306b\u306f\u3001(1)\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u3084NK\u7d30\u80de\u7b49\u306e\u8caa\u98df\u7d30\u80de\u304c\u4e2d\u5fc3\u3068\u306a\u308b\u8caa\u98df\u3001(2)\u88dc\u4f53\u30ec\u30af\u30c1\u30f3\u7d4c\u8def\u3001(3)\u597d\u4e2d\u7403\u7d30\u80de\u5916\u30c8\u30e9\u30c3\u30d7\u304c\u3042\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u88dc\u4f53\u30ec\u30af\u30c1\u30f3\u7d4c\u8def\u306b\u304a\u3044\u3066\u306f\u3001Mannose Binding Lect<\/p><\/div>\n

\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-2079","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/2079","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=2079"}],"version-history":[{"count":7,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/2079\/revisions"}],"predecessor-version":[{"id":2089,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/2079\/revisions\/2089"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=2079"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=2079"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=2079"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}