{"id":1785,"date":"2021-01-16T09:17:29","date_gmt":"2021-01-16T00:17:29","guid":{"rendered":"http:\/\/www.emukk.com\/WP\/?p=1785"},"modified":"2021-07-21T23:42:16","modified_gmt":"2021-07-21T14:42:16","slug":"%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9sars-cov-2%ef%bc%89%e3%81%ae%e5%89%8d%e9%a7%86%e4%bd%93%e3%82%bf%e3%83%b3%e3%83%91%e3%82%af%e8%b3%aa%e5%88%87%e6%96%ad","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9sars-cov-2%ef%bc%89%e3%81%ae%e5%89%8d%e9%a7%86%e4%bd%93%e3%82%bf%e3%83%b3%e3%83%91%e3%82%af%e8%b3%aa%e5%88%87%e6%96%ad\/","title":{"rendered":"\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u306e\u524d\u99c6\u4f53\u30bf\u30f3\u30d1\u30af\u8cea\u5207\u65ad\u9175\u7d20\uff08\u30e1\u30a4\u30f3\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc: Mpro<\/sup>\uff09\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u3057\u305f\u690d\u7269\u7531\u6765\u6210\u5206\u306e\u963b\u5bb3\u5264\u3068\u3057\u3066\u306e\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0"},"content":{"rendered":"

\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9 (SARS-CoV-2) \u304c\u5bbf\u4e3b\u7d30\u80de\u306b\u611f\u67d3\u3059\u308b\u3068\u3001\u30a6\u30a4\u30eb\u30b9\u7531\u6765\u306eRNA\u304b\u3089\u5de8\u5927\u306a\u524d\u99c6\u4f53\u30bf\u30f3\u30d1\u30af\u304c\u5408\u6210\u3055\u308c\u307e\u3059\u3002\u305d\u306e\u524d\u99c6\u4f53\u30bf\u30f3\u30d1\u30af\u306f\u7a2e\u3005\u306e\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc\u306b\u3088\u3063\u3066\u5207\u65ad\u3055\u308c\u3001\u30a6\u30a4\u30eb\u30b9\u306e\u5897\u6b96\u306b\u5fc5\u8981\u306a\u6a5f\u80fd\u30bf\u30f3\u30d1\u30af\u3068\u306a\u308a\u307e\u3059\u3002\u30e1\u30a4\u30f3\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc\uff08Mpro<\/sup>)\u306f\u3001\u524d\u99c6\u4f53\u30bf\u30f3\u30d1\u30af\u8cea\u5207\u65ad\u9175\u7d20\u306e\u3072\u3068\u3064\u3067\u3042\u308a\u3001\u30a6\u30a4\u30eb\u30b9\u306e\u5897\u6b96\u306b\u5fc5\u8981\u4e0d\u53ef\u6b20\u306a\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc\u3067\u3059\u3002<\/p>\n

Univ. of Medical Sciences and Technology, Khartoum, Sudan\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u3053\u306e\u30e1\u30a4\u30f3\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3057\u3066\u3001\u30b9\u30fc\u30c0\u30f3\u306e\u4f1d\u7d71\u7684\u306a\u533b\u85ac\u54c1\u3068\u3057\u3066\u4f7f\u308f\u308c\u3066\u3044\u308b\u690d\u7269\u7531\u6765\u306e\u6210\u5206\u306b\u3064\u3044\u3066\u3001\u5206\u5b50\u30c9\u30c3\u30ad\u30f3\u30b0\u30fb\u5206\u5b50\u52d5\u529b\u5b66\u7684\u30b7\u30df\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u306b\u3088\u3063\u3066\u3001\u305d\u306e\u963b\u5bb3\u52b9\u679c\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002
\nhttps:\/\/link.springer.com\/article\/10.1007\/s40203-020-00073-8<\/a><\/p>\n

\u7d50\u679c\u3001\u4e0b\u8a18\u306e\u690d\u7269\u7531\u6765\u6210\u5206\u304c\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\u963b\u5bb3\u5264\u3068\u3057\u3066\u671f\u5f85\u3055\u308c\u307e\u3059\u3002in vivo\u3067\u306e\u8a55\u4fa1\u3092\u671f\u5f85\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n\n\n\n\n\n
Name<\/td>\nEnergy (kcal\/mol)<\/td>\nPredicted LD50 mg\/kg<\/td>\n<\/tr>\n
Gallic acid<\/td>\n\u2212 17.45<\/td>\n2260<\/td>\n<\/tr>\n
Quercetin<\/td>\n\u2212 15.81<\/td>\n159<\/td>\n<\/tr>\n
Naringin<\/td>\n\u2212 14.50<\/td>\n2300<\/td>\n<\/tr>\n
Capsaicin<\/td>\n\u2212 13.90<\/td>\n 47<\/td>\n<\/tr>\n
Psychotrine<\/td>\n\u2212 13.50<\/td>\n480<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9 (SARS-CoV-2) \u304c\u5bbf\u4e3b\u7d30\u80de\u306b\u611f\u67d3\u3059\u308b\u3068\u3001\u30a6\u30a4\u30eb\u30b9\u7531\u6765\u306eRNA\u304b\u3089\u5de8\u5927\u306a\u524d\u99c6\u4f53\u30bf\u30f3\u30d1\u30af\u304c\u5408\u6210\u3055\u308c\u307e\u3059\u3002\u305d\u306e\u524d\u99c6\u4f53\u30bf\u30f3\u30d1\u30af\u306f\u7a2e\u3005\u306e\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc\u306b\u3088\u3063\u3066\u5207\u65ad\u3055\u308c\u3001\u30a6\u30a4\u30eb\u30b9\u306e\u5897\u6b96\u306b\u5fc5\u8981\u306a\u6a5f\u80fd\u30bf\u30f3\u30d1\u30af<\/p><\/div>\n

\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-1785","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/1785","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=1785"}],"version-history":[{"count":11,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/1785\/revisions"}],"predecessor-version":[{"id":5160,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/1785\/revisions\/5160"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=1785"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=1785"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=1785"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}