{"id":1762,"date":"2021-01-12T11:33:28","date_gmt":"2021-01-12T02:33:28","guid":{"rendered":"http:\/\/www.emukk.com\/WP\/?p=1762"},"modified":"2021-07-21T23:42:56","modified_gmt":"2021-07-21T14:42:56","slug":"banlec%ef%bc%88%e3%83%ac%e3%82%af%e3%83%81%e3%83%b3%ef%bc%89%e3%81%8c%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88sars-cov-2%ef%bc%89%e3%81%ab%e5%af%be","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/banlec%ef%bc%88%e3%83%ac%e3%82%af%e3%83%81%e3%83%b3%ef%bc%89%e3%81%8c%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88sars-cov-2%ef%bc%89%e3%81%ab%e5%af%be\/","title":{"rendered":"BanLec\uff08\u30ec\u30af\u30c1\u30f3\uff09\u304c\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u306b\u5bfe\u3059\u308b\u6297\u30a6\u30a4\u30eb\u30b9\u85ac\u3068\u3057\u3066\u306e\u6f5c\u5728\u6027\u3092\u793a\u3059"},"content":{"rendered":"<p>\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u306b\u306f\u300122\u500b\u306eN-\u578b\u7cd6\u9396\u4fee\u98fe\u90e8\u4f4d\u304c\u3042\u308b\u3068\u3044\u3046\u3053\u3068\u304c\u65e2\u306b\u793a\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u4f8b\u3048\u3070\u3001<a href=\"https:\/\/science.sciencemag.org\/content\/369\/6501\/330.long\">https:\/\/science.sciencemag.org\/content\/369\/6501\/330.long<\/a>\u3092\u53c2\u7167\u306e\u3053\u3068\uff09\u3002<\/p>\n<p>SARS-CoV-2\u306f\u3001ACE2\u53d7\u5bb9\u4f53\u306b\u5f37\u304f\u7d50\u5408\u3059\u308b\u3068\u3044\u3046\u3053\u3068\u304b\u3089\u3001S\u30bf\u30f3\u30d1\u30af\u8cea\u306eS1\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u5185\u306b\u5b58\u5728\u3059\u308bRBD\u306eAsn343\u306b\u5b58\u5728\u3059\u308b\u7cd6\u9396\uff08Man3GlcNAc2Fuc\uff09\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3057\u3066\u3001Mannose\u53ca\u3073GlcNAc\u7279\u7570\u7684\u306a\u30ec\u30af\u30c1\u30f3\u306e\u7d50\u5408\u5f37\u5ea6\u3092\u5206\u5b50\u30c9\u30c3\u30ad\u30f3\u30b0\u30fb\u5206\u5b50\u52d5\u529b\u5b66\u30b7\u30e5\u30df\u30ec\u30fc\u30b7\u30e7\u30f3\u3092\u7528\u3044\u3066\u8a08\u7b97\u3057\u3001\u6297\u30a6\u30a4\u30eb\u30b9\u8a66\u85ac\u3068\u3057\u3066\u306e\u6f5c\u5728\u7684\u306a\u8a55\u4fa1\u3092\u884c\u3044\u307e\u3057\u305f\u3002<br \/>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33292056\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33292056\/<\/a><\/p>\n<p>\u6bd4\u8f03\u3057\u305f\u30ec\u30af\u30c1\u30f3\u306f\u6b21\u306e\u901a\u308a\u3067\u3042\u308a\u3001BanLec\u304c\u4e00\u756a\u9ad8\u3044\u7d50\u5408\u529b\u3092\u793a\u3057\u305f\u3068\u306e\u3053\u3068\u3067\u3059\u3002<br \/>\nBanLec\uff1a -105.99kcal\/mol<br \/>\nNPA\uff1a -79kcal\/mol<br \/>\nGRFT\uff1a -73.7kcal\/mol<br \/>\nCV-N\uff1a -67.3kcal\/mol<br \/>\nUDA\uff1a -98.3kcal\/mol<\/p>\n<p>\u30ec\u30af\u30c1\u30f3\u306f\u3001\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u4e00\u822c\u7684\u306b\u3001\u5909\u7570\u539f\u6027\u3001\u8840\u7403\u51dd\u96c6\u3001\u708e\u75c7\u3089\u306e\u526f\u4f5c\u7528\u3092\u793a\u3059\u305f\u3081\u3001in vivo\u3067\u306e\u78ba\u8a8d\u304c\u5fc5\u8981\u4e0d\u53ef\u6b20\u3067\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08SARS-CoV-2\uff09\u306b\u306f\u300122\u500b\u306eN-\u578b\u7cd6\u9396\u4fee\u98fe\u90e8\u4f4d\u304c\u3042\u308b\u3068\u3044\u3046\u3053\u3068\u304c\u65e2\u306b\u793a\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u4f8b\u3048\u3070\u3001https:\/\/science.sciencemag.org\/content\/369\/6501\/33<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/banlec%ef%bc%88%e3%83%ac%e3%82%af%e3%83%81%e3%83%b3%ef%bc%89%e3%81%8c%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88sars-cov-2%ef%bc%89%e3%81%ab%e5%af%be\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-1762","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/1762","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=1762"}],"version-history":[{"count":6,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/1762\/revisions"}],"predecessor-version":[{"id":2633,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/1762\/revisions\/2633"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=1762"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=1762"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=1762"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}