{"id":15017,"date":"2024-10-30T08:13:43","date_gmt":"2024-10-29T23:13:43","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=15017"},"modified":"2024-10-30T08:17:59","modified_gmt":"2024-10-29T23:17:59","slug":"sars-cov-2-antiviral-activities-using-vegetable-exosomes","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/en\/sars-cov-2-antiviral-activities-using-vegetable-exosomes\/","title":{"rendered":"SARS-CoV-2 antiviral activities using vegetable exosomes"},"content":{"rendered":"<p>A group from Nebraska Center for Virology, University of Nebraska-Lincoln, NE 68583, USA\u3000has reported about a new lectin found from shiitake exosomes.<br \/>\n<a href=\"https:\/\/www.mdpi.com\/1999-4915\/16\/10\/1546\">https:\/\/www.mdpi.com\/1999-4915\/16\/10\/1546<\/a><\/p>\n<p>Exosomes from fifteen local common vegetables were isolated by ultracentrifugation. These exosomes were evaluated for their antiviral activities against SARS-CoV-2 infection using an in vitro pseudovirus platform.<br \/>\nTheir cytotoxicity using the standard MTT method indicated that all fifteen samples did not show significant cytotoxicity in a concentration of 1 \u00d7 10^10\/mL exosomes. The antiviral activities of shiitake exosomes exhibited the lowest EC<sub>50<\/sub> value 5.2 \u00d7 10^8\/mL.<br \/>\nFrom the proteomic analysis of the exosomes, it was found that a lectin (named Shictin) of shiitake exosomes Contributed to the Antiviral Activities and exhibited strong activity against the SARS-CoV-2 Omicron variant with an IC<sub>50<\/sub> value of 87 nM. It was also found that shictin is a C-type lectin and binds to GlcNAc.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A group from Nebraska Center for Virology, University of Nebraska-Lincoln, NE 68583, USA\u3000has reported about a <\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/en\/sars-cov-2-antiviral-activities-using-vegetable-exosomes\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-15017","post","type-post","status-publish","format-standard","hentry","category-technology-en"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/15017","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=15017"}],"version-history":[{"count":2,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/15017\/revisions"}],"predecessor-version":[{"id":15019,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/15017\/revisions\/15019"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=15017"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=15017"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=15017"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}