{"id":14469,"date":"2024-03-29T08:24:26","date_gmt":"2024-03-28T23:24:26","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=14469"},"modified":"2024-03-29T08:29:32","modified_gmt":"2024-03-28T23:29:32","slug":"changes-in-glycosylation-in-pancreatic-ductal-adenocarcinoma-mediated-by-kras-mutations","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/en\/changes-in-glycosylation-in-pancreatic-ductal-adenocarcinoma-mediated-by-kras-mutations\/","title":{"rendered":"Changes in glycosylation in Pancreatic Ductal Adenocarcinoma mediated by KRAS mutations"},"content":{"rendered":"<p>A group from Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tsukuba, Japan, etc. has reported about changes in glycosylation in Pancreatic Ductal Adenocarcinoma mediated by KRAS gene mutations.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10963106\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10963106\/<\/a><\/p>\n<p>It was shown that Fucosilation and mannosylation were upregurated in pancreatin ductal adenocarcinoma with KRAS gene mutations.<br \/>\nThe lectins enriched in KRAS mutants included fucose-binding lectins (AAL, rAAL, AOL, rAOL, rRSIIL, and UEAI) and mannose-binding lectins (rRSL, rBC2LCA, rPAIIL, and NPA).<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2024\/03\/KRAS-mutation.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2024\/03\/KRAS-mutation-300x113.png\" alt=\"\" width=\"300\" height=\"113\" class=\"alignnone size-medium wp-image-14467\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2024\/03\/KRAS-mutation-300x113.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2024\/03\/KRAS-mutation-600x226.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2024\/03\/KRAS-mutation-230x87.png 230w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2024\/03\/KRAS-mutation-350x132.png 350w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2024\/03\/KRAS-mutation-480x181.png 480w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2024\/03\/KRAS-mutation.png 716w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A group from Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, Univer<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/en\/changes-in-glycosylation-in-pancreatic-ductal-adenocarcinoma-mediated-by-kras-mutations\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70],"tags":[],"class_list":["post-14469","post","type-post","status-publish","format-standard","hentry","category-nature-en"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/14469","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=14469"}],"version-history":[{"count":1,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/14469\/revisions"}],"predecessor-version":[{"id":14470,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/14469\/revisions\/14470"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=14469"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=14469"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=14469"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}