{"id":13798,"date":"2023-11-14T07:45:09","date_gmt":"2023-11-13T22:45:09","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=13798"},"modified":"2023-11-14T07:53:07","modified_gmt":"2023-11-13T22:53:07","slug":"gal-modification-of-laminin-receptor-integrin-%ce%b16%ce%b21-is-reduced-in-hepatocellular-carcinoma-and-thereby-accelerates-cancer-cell-invasion","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/en\/gal-modification-of-laminin-receptor-integrin-%ce%b16%ce%b21-is-reduced-in-hepatocellular-carcinoma-and-thereby-accelerates-cancer-cell-invasion\/","title":{"rendered":"Gal modification of laminin receptor integrin \u03b16\u03b21 is reduced in hepatocellular carcinoma, and thereby accelerates cancer cell invasion"},"content":{"rendered":"<p>A group from Graduate Institute of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan, etc. has reported that Beta1,4-galactosyltransferases (B4GALTs) downregulation upregurates agalacto N-glycans and enhances the laminin-binding activity of integrin \u03b16 and integrin \u03b21 to promote invasiveness of Hepatocellular carcinoma (HCC) cells.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10618527\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10618527\/<\/a><\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/11\/HCC-Gal.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-13795\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/11\/HCC-Gal-300x227.jpg\" alt=\"\" width=\"300\" height=\"227\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/11\/HCC-Gal-300x227.jpg 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/11\/HCC-Gal-600x454.jpg 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/11\/HCC-Gal-230x174.jpg 230w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/11\/HCC-Gal-350x265.jpg 350w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/11\/HCC-Gal-480x363.jpg 480w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/11\/HCC-Gal.jpg 675w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A group from Graduate Institute of Anatomy and Cell Biology, College of Medicine, National Taiwan University, <\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/en\/gal-modification-of-laminin-receptor-integrin-%ce%b16%ce%b21-is-reduced-in-hepatocellular-carcinoma-and-thereby-accelerates-cancer-cell-invasion\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70],"tags":[],"class_list":["post-13798","post","type-post","status-publish","format-standard","hentry","category-nature-en"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/13798","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=13798"}],"version-history":[{"count":2,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/13798\/revisions"}],"predecessor-version":[{"id":13801,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/13798\/revisions\/13801"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=13798"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=13798"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=13798"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}