{"id":13643,"date":"2023-10-09T07:11:44","date_gmt":"2023-10-08T22:11:44","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=13643"},"modified":"2023-10-09T07:11:44","modified_gmt":"2023-10-08T22:11:44","slug":"%e8%b1%9a%e9%9e%ad%e8%99%ab%e3%81%ae%e6%8e%92%e6%b3%84%ef%bd%b0%e5%88%86%e6%b3%8c%e7%89%a9%e3%81%aen-%e5%9e%8b%e7%b3%96%e9%8e%96%e3%81%a8%e5%85%8d%e7%96%ab%e7%b3%bb%e3%81%a8%e3%81%ae%e7%9b%b8%e4%ba%92","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e8%b1%9a%e9%9e%ad%e8%99%ab%e3%81%ae%e6%8e%92%e6%b3%84%ef%bd%b0%e5%88%86%e6%b3%8c%e7%89%a9%e3%81%aen-%e5%9e%8b%e7%b3%96%e9%8e%96%e3%81%a8%e5%85%8d%e7%96%ab%e7%b3%bb%e3%81%a8%e3%81%ae%e7%9b%b8%e4%ba%92\/","title":{"rendered":"\u8c5a\u97ad\u866b\u306e\u6392\u6cc4\uff70\u5206\u6ccc\u7269\u306eN-\u578b\u7cd6\u9396\u3068\u514d\u75ab\u7cfb\u3068\u306e\u76f8\u4e92\u4f5c\u7528"},"content":{"rendered":"<p>Institut f\u00fcr Biochemie, Department f\u00fcr Chemie, Universit\u00e4t f\u00fcr Bodenkultur, Wien, Austria\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u8c5a\u97ad\u866b\u306eN-\u578b\u7cd6\u9396\u3068\u514d\u75ab\u7cfb\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10542551\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10542551\/<\/a><\/p>\n<p>\u672c\u7814\u7a76\u3067\u306f\u3001\u8c5a\u7dda\u866b\u5bc4\u751f\u866b\uff08\u8c5a\u97ad\u866b\uff09\u7531\u6765\u306eN-\u578b\u7cd6\u9396 (27 \u7a2e) \u3092\u7528\u3044\u305f\u5929\u7136\u578b\u7cd6\u9396\u30de\u30a4\u30af\u30ed\u30a2\u30ec\u30a4\u3092\u958b\u767a\u3057\u3001\u3053\u308c\u3089\u306e\u7cd6\u9396\u3068C-\u578b\u30ec\u30af\u30c1\u30f3 (DC-SIGN\u3001Dectin-2\u3001MGL) \u306a\u3069\u3068\u306e\u76f8\u4e92\u4f5c\u7528\u304c\u8a55\u4fa1\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5f97\u3089\u308c\u305f N-\u578b\u7cd6\u9396\u306f\u3001\u30db\u30b9\u30db\u30ea\u30eb\u30b3\u30ea\u30f3\u4fee\u98fe\u542b\u3080\u3001\u307e\u305f\u306f\u542b\u307e\u306a\u3044\u30d5\u30b3\u30b7\u30eb\u5316LacdiNAc\u69cb\u9020 (bi\/tri\/tetra-anttenary) \u3068\u30db\u30b9\u30db\u30ea\u30eb\u30b3\u30ea\u30f3\u4fee\u98fe\u3092\u53d7\u3051\u305f\u30aa\u30ea\u30b4\u30de\u30f3\u30ce\u30fc\u30b9\u69cb\u9020\u3067\u3057\u305f\u3002<\/p>\n<p>DC-SIGN\u306f\u3001\u304b\u306a\u308a\u5e83\u7bc4\u56f2\u306e\u30aa\u30ea\u30b4\u30de\u30f3\u30aa\u30fc\u30b9\u304a\u3088\u3073\u30d5\u30b3\u30b7\u30eb\u5316\u7cd6\u9396\u3092\u8a8d\u8b58\u3057\u307e\u3057\u305f\u304c\u3001\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3068\u3057\u3066\u7528\u3044\u3089\u308c\u305fMan5-9GlcNAc2\u306b\u3082\u826f\u304f\u7d50\u5408\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\nDectin-2\u306f\u3001\u4ed6\u306e\u81ea\u7136\u514d\u75ab\u7cfb\u30ec\u30af\u30c1\u30f3\u3068\u6bd4\u8f03\u3057\u3066\u672c\u30a2\u30ec\u30a4\u4e0a\u3067\u306f\u7d50\u5408\u304c\u975e\u5e38\u306b\u5f31\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002<br \/>\nMGL\u306f\u3001LacdiNAc\u542b\u6709\u30ea\u30ac\u30f3\u30c9\u306e\u30db\u30b9\u30db\u30ea\u30eb\u30b3\u30ea\u30f3\u4fee\u98fe\u306e\u5b58\u5728\u306b\u95a2\u4fc2\u306a\u304f\u3001\u5927\u90e8\u5206\u306e\u672c\u7cd6\u9396\u69cb\u9020\u306b\u7d50\u5408\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/10\/T.-suis-N-glycans.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-13644\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/10\/T.-suis-N-glycans-300x217.png\" alt=\"\" width=\"300\" height=\"217\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/10\/T.-suis-N-glycans-300x217.png 300w, 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