{"id":13587,"date":"2023-09-25T09:05:41","date_gmt":"2023-09-25T00:05:41","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=13587"},"modified":"2023-09-25T14:20:25","modified_gmt":"2023-09-25T05:20:25","slug":"st3gal5%e3%82%92%e9%ab%98%e7%99%ba%e7%8f%be%e3%81%99%e3%82%8b%e3%81%8c%e3%82%93%e7%b4%b0%e8%83%9e%e3%81%8b%e3%82%89%e5%88%86%e6%b3%8c%e3%81%95%e3%82%8c%e3%82%8b%e3%82%a8%e3%82%ad%e3%82%bd%e3%82%bd","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/st3gal5%e3%82%92%e9%ab%98%e7%99%ba%e7%8f%be%e3%81%99%e3%82%8b%e3%81%8c%e3%82%93%e7%b4%b0%e8%83%9e%e3%81%8b%e3%82%89%e5%88%86%e6%b3%8c%e3%81%95%e3%82%8c%e3%82%8b%e3%82%a8%e3%82%ad%e3%82%bd%e3%82%bd\/","title":{"rendered":"ST3GAL5\u3092\u9ad8\u767a\u73fe\u3059\u308b\u304c\u3093\u7d30\u80de\u304b\u3089\u5206\u6ccc\u3055\u308c\u308b\u30a8\u30ad\u30bd\u30bd\u30fc\u30e0\u304c\u3001\u304c\u3093\u306e\u8179\u819c\u64ad\u7a2e\u3092\u4fc3\u9032\u3059\u308b"},"content":{"rendered":"<p>\u79cb\u7530\u5927\u5b66\u533b\u5b66\u90e8\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30e9\u30af\u30c8\u30b7\u30eb\u30bb\u30e9\u30df\u30c9 \u03b1-2,3-\u30b7\u30a2\u30ea\u30eb\u7cd6\u8ee2\u79fb\u9175\u7d20\uff08ST3G5\uff09\u304c\u3001ST3G5\u304c\u9ad8\u767a\u73fe\u3057\u3066\u3044\u308b\u304c\u3093\u7d30\u80de\u304b\u3089\u5206\u6ccc\u3055\u308c\u308b\u30a8\u30ad\u30bd\u30bd\u30fc\u30e0\u306b\u3088\u3063\u3066\u5a92\u4ecb\u3055\u308c\u308b\u8179\u819c\u64ad\u7a2e\u3092\u4e88\u9632\u3059\u308b\u305f\u3081\u306e\u9069\u5207\u306a\u5275\u85ac\u6a19\u7684\u3068\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37716915\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37716915\/<\/a><\/p>\n<p>\u672c\u8ad6\u6587\u3067\u306f\u3001\u8179\u819c\u4e73\u72b6\u6591\u70b9\u306b\u304a\u3051\u308b\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u306b\u3088\u3063\u3066\u5a92\u4ecb\u3055\u308c\u308b\u524d\u8ee2\u79fb\u5fae\u5c0f\u74b0\u5883\u306b\u304a\u3051\u308bST3G5\uff08ST3GAL5 \u304a\u3088\u3073GM3\u5408\u6210\u9175\u7d20\u3068\u3082\u547c\u3070\u308c\u308b) \u306e\u5f79\u5272\u306b\u3064\u3044\u3066\u7814\u7a76\u304c\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>ST3G5\u304c\u9ad8\u767a\u73fe\u3059\u308b\u304c\u3093\u7d30\u80de\uff08ST3G5high-cExos\uff09\u304b\u3089\u5206\u6ccc\u3055\u308c\u308b\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u306b\u306f\u3001\u9ad8\u30ec\u30d9\u30eb\u306e\u4f4e\u9178\u7d20\u8a98\u5c0e\u56e0\u5b501-\u03b1\uff08HIF1\u03b1\uff09\u3068\u89e3\u7cd6\u7cfb\u9175\u7d20\u304c\u542b\u307e\u308c\u3066\u304a\u308a\u3001\u30b7\u30a2\u30eb\u9178\u7d50\u5408\u6027\u306eGM3\u53d7\u5bb9\u4f53\u3067\u3042\u308bCD169\uff08Siglec1\u3068\u3082\u547c\u3070\u308c\u308b\uff09\u306e\u767a\u73fe\u4e0a\u6607\u306b\u3088\u308b\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u3067\u306e\u53d6\u308a\u8fbc\u307f\u3092\u4ecb\u3057\u3066\u3001\u8179\u819c\u4e73\u72b6\u6591\u70b9\u306b\u84c4\u7a4d\u3055\u308c\u308b\u3053\u3068\u304c\u5224\u660e\u3057\u307e\u3057\u305f\u3002CD169\u306e\u767a\u73fe\u4e0a\u6607\u306f\u3001\u6b63\u306e\u30d5\u30a3\u30fc\u30c9\u30d0\u30c3\u30af\u30eb\u30fc\u30d7\u3092\u4ecb\u3057\u3066\u66f4\u306a\u308b\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u306e\u53d6\u308a\u8fbc\u307f\u3092\u4fc3\u9032\u3057\u307e\u3059\u3002<br \/>\n\u5c1a\u3001GM3\u306f\u3001ST3G5\u306b\u3088\u308b\u30b7\u30a2\u30eb\u9178\u306e\u30e9\u30af\u30c8\u30b7\u30eb\u30bb\u30e9\u30df\u30c9\u3078\u306e\u8ee2\u79fb\u4fee\u98fe\u306b\u3088\u3063\u3066\u5f62\u6210\u3055\u308c\u308b\u30ac\u30f3\u30b0\u30ea\u30aa\u30b7\u30c9\u30d5\u30a1\u30df\u30ea\u30fc\u751f\u5408\u6210\u306b\u304a\u3051\u308b\u6700\u521d\u306e\u5206\u5b50\u3067\u3001\u7d30\u80de\u306e\u63a5\u7740\u3001\u5897\u6b96\u3001\u304a\u3088\u3073\u904a\u8d70\u3092\u8abf\u7bc0\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u304a\u308a\u3001HIF1\u03b1\u306f\u3001\u8179\u819c\u4e73\u72b6\u6591\u70b9\u306b\u304a\u3051\u308b\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u5206\u5b50\uff08PD-L1\uff09\u306e\u767a\u73fe\u3092\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n<p>\u3053\u308c\u3089\u306e\u7d50\u679c\u306f\u3001ST3G5 \u304c\u4e00\u90e8\u306e\u764c\u306b\u304a\u3051\u308b\u8179\u819c\u64ad\u7a2e\u3092\u4e88\u9632\u3059\u308b\u305f\u3081\u306e\u6709\u671b\u306a\u5275\u85ac\u6a19\u7684\u306b\u6210\u308a\u5f97\u308b\u3053\u3068\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u79cb\u7530\u5927\u5b66\u533b\u5b66\u90e8\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30e9\u30af\u30c8\u30b7\u30eb\u30bb\u30e9\u30df\u30c9 \u03b1-2,3-\u30b7\u30a2\u30ea\u30eb\u7cd6\u8ee2\u79fb\u9175\u7d20\uff08ST3G5\uff09\u304c\u3001ST3G5\u304c\u9ad8\u767a\u73fe\u3057\u3066\u3044\u308b\u304c\u3093\u7d30\u80de\u304b\u3089\u5206\u6ccc\u3055\u308c\u308b\u30a8\u30ad\u30bd\u30bd\u30fc\u30e0\u306b\u3088\u3063\u3066\u5a92\u4ecb\u3055\u308c\u308b\u8179\u819c\u64ad\u7a2e\u3092\u4e88\u9632\u3059\u308b\u305f\u3081\u306e\u9069\u5207\u306a\u5275\u85ac\u6a19\u7684\u3068\u306a\u308b<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/st3gal5%e3%82%92%e9%ab%98%e7%99%ba%e7%8f%be%e3%81%99%e3%82%8b%e3%81%8c%e3%82%93%e7%b4%b0%e8%83%9e%e3%81%8b%e3%82%89%e5%88%86%e6%b3%8c%e3%81%95%e3%82%8c%e3%82%8b%e3%82%a8%e3%82%ad%e3%82%bd%e3%82%bd\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-13587","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/13587","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=13587"}],"version-history":[{"count":14,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/13587\/revisions"}],"predecessor-version":[{"id":13608,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/13587\/revisions\/13608"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=13587"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=13587"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=13587"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}