{"id":12597,"date":"2023-04-16T06:42:04","date_gmt":"2023-04-15T21:42:04","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=12597"},"modified":"2023-04-16T06:42:04","modified_gmt":"2023-04-15T21:42:04","slug":"%e7%b7%9a%e7%b6%ad%e8%8a%bd%e7%b4%b0%e8%83%9e%e5%a2%97%e6%ae%96%e5%9b%a0%e5%ad%90%e5%8f%97%e5%ae%b9%e4%bd%93%e3%81%aen-%e5%9e%8b%e7%b3%96%e9%8e%96%e3%81%b8%e3%81%ae%e3%82%ac%e3%83%ac%e3%82%af%e3%83%81","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e7%b7%9a%e7%b6%ad%e8%8a%bd%e7%b4%b0%e8%83%9e%e5%a2%97%e6%ae%96%e5%9b%a0%e5%ad%90%e5%8f%97%e5%ae%b9%e4%bd%93%e3%81%aen-%e5%9e%8b%e7%b3%96%e9%8e%96%e3%81%b8%e3%81%ae%e3%82%ac%e3%83%ac%e3%82%af%e3%83%81\/","title":{"rendered":"\u7dda\u7dad\u82bd\u7d30\u80de\u5897\u6b96\u56e0\u5b50\u53d7\u5bb9\u4f53\u306eN-\u578b\u7cd6\u9396\u3078\u306e\u30ac\u30ec\u30af\u30c1\u30f3\u306e\u7d50\u5408\u304c\u7d30\u80de\u6d3b\u6027\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059"},"content":{"rendered":"

Department of Protein Engineering, Faculty of Biotechnology, University of Wroclaw, Poland\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30ac\u30ec\u30af\u30c1\u30f3\uff08Gal-1, Gal-3, Gal-7, Gal-8)\u304c\u7dda\u7dad\u82bd\u7d30\u80de\u5897\u6b96\u56e0\u5b50\u53d7\u5bb9\u4f53\uff08FGFR\uff09\u306eN-\u578b\u7cd6\u9396\u306b\u7d50\u5408\u3059\u308b\u3053\u3068\u306b\u3088\u308aFGFR\u306e\u30af\u30e9\u30b9\u30bf\u30ea\u30f3\u30b0\u304c\u8d77\u3053\u308a\u3001\u305d\u306e\u4e0b\u6d41\u306b\u3042\u308b\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u30ab\u30b9\u30b1\u30fc\u30c9\u3092\u6d3b\u6027\u5316\u3059\u308b\u3068\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002
\nhttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10070233\/<\/a><\/p>\n

\u30ac\u30ec\u30af\u30c1\u30f3\u306f\u53d7\u5bb9\u4f53\u3078\u306e\u76f4\u63a5\u4f5c\u7528\u3092\u901a\u3058\u3066 FGF\/FGFR \u7d30\u80de\u30d7\u30ed\u30bb\u30b9\u3092\u8abf\u7bc0\u3057\u3001\u30ac\u30ec\u30af\u30c1\u30f3\u8a98\u5c0e FGFR \u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u306e\u7d30\u80de\u3078\u306e\u5f71\u97ff\u306f\u3001\u6a19\u6e96\u30ea\u30ac\u30f3\u30c9 (FGF) \u306b\u3088\u3063\u3066\u9054\u6210\u3055\u308c\u308b\u3082\u306e\u3068\u306f\u5927\u304d\u304f\u7570\u306a\u308b\u3053\u3068\u304c\u5b9f\u8a3c\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

Gal-1\u3001-3\u3001-7\u3001\u304a\u3088\u3073-8\u306f\u3001\u30d2\u30c8\u30ac\u30ec\u30af\u30c1\u30f3\u306e\u4e2d\u3067FGFR\uff08FGFR1\uff5eFGFR4\uff09\u306e\u6700\u3082\u52b9\u679c\u7684\u306a\u30d0\u30a4\u30f3\u30c0\u30fc\u3067\u3042\u308a\u3001\u30ac\u30ec\u30af\u30c1\u30f3\u306e\u591a\u4fa1\u6027\u306b\u3088\u3063\u3066\u8a98\u8d77\u3055\u308c\u308bFGFR1\u306e\u30af\u30e9\u30b9\u30bf\u30ea\u30f3\u30b0\u304c\u3001FGFR1\u306e\u6d3b\u6027\u5316\u3068\u305d\u306e\u4e0b\u6d41\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u30ab\u30b9\u30b1\u30fc\u30c9\u306e\u6d3b\u6027\u5316\u306b\u4e0d\u53ef\u6b20\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002\u8208\u5473\u6df1\u3044\u3053\u3068\u306b\u3001Gal-1\u3001-3\u3001\u304a\u3088\u3073-8 \u3068 FGF1 \u304c\u5354\u8abf\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u500b\u3005\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u4f5c\u7528\u3059\u308b\u3088\u308a\u3082\u52b9\u679c\u7684\u306b\u751f\u5b58\u7d30\u80de\u6570\u304c\u5897\u52a0\u3057\u307e\u3057\u305f\u3002\u66f4\u306b\u3001FGF1 \u3068Gal-1 \u304a\u3088\u3073Gal-3\u304c\u5354\u8abf\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u305d\u308c\u305e\u308c\u306e\u5358\u4e00\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u4f5c\u7528\u3057\u305f\u5834\u5408\u3068\u6bd4\u8f03\u3057\u3066\u3001\u30b0\u30eb\u30b3\u30fc\u30b9\u306e\u53d6\u308a\u8fbc\u307f\u304c\u5897\u5f37\u3055\u308c\u308b\u3053\u3068\u3082\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\"\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Department of Protein Engineering, Faculty of Biotechnology, University of Wroclaw, Poland\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30ac\u30ec\u30af\u30c1\u30f3\uff08Gal-1,<\/p><\/div>\n

\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-12597","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/12597","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=12597"}],"version-history":[{"count":6,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/12597\/revisions"}],"predecessor-version":[{"id":12604,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/12597\/revisions\/12604"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=12597"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=12597"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=12597"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}