{"id":12447,"date":"2023-03-12T08:26:59","date_gmt":"2023-03-11T23:26:59","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=12447"},"modified":"2023-03-12T10:08:03","modified_gmt":"2023-03-12T01:08:03","slug":"%e3%83%a1%e3%83%a9%e3%83%8e%e3%83%bc%e3%83%9e%e3%81%ae%e7%89%b9%e7%95%b0%e7%9a%84%e3%81%aa%e7%b3%96%e9%8e%96%e4%bf%ae%e9%a3%be%e5%a4%89%e5%8c%96%e3%81%8c%e6%a8%b9%e7%8a%b6%e7%b4%b0%e8%83%9e%e3%81%ae","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e3%83%a1%e3%83%a9%e3%83%8e%e3%83%bc%e3%83%9e%e3%81%ae%e7%89%b9%e7%95%b0%e7%9a%84%e3%81%aa%e7%b3%96%e9%8e%96%e4%bf%ae%e9%a3%be%e5%a4%89%e5%8c%96%e3%81%8c%e6%a8%b9%e7%8a%b6%e7%b4%b0%e8%83%9e%e3%81%ae\/","title":{"rendered":"\u30e1\u30e9\u30ce\u30fc\u30de\u306e\u7279\u7570\u7684\u306a\u7cd6\u9396\u4fee\u98fe\u5909\u5316\u304c\u6a39\u72b6\u7d30\u80de\u306e\u514d\u75ab\u6d3b\u6027\u306b\u4e0e\u3048\u308b\u5f71\u97ff"},"content":{"rendered":"<p>Institute for Advanced Biosciences, Universit\u00e9 Grenoble Alpes, Grenoble, France\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30e1\u30e9\u30ce\u30fc\u30de\u306e\u7cd6\u9396\u4fee\u98fe\u306e\u5909\u5316\u3068\u305d\u306e\u6a39\u72b6\u7d30\u80de\u306e\u514d\u75ab\u6d3b\u6027\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9986448\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9986448\/<\/a><\/p>\n<p>\u30e1\u30e9\u30ce\u30fc\u30de\u60a3\u8005\u306e\u816b\u760d\u7d30\u80de\u306b\u304a\u3044\u3066\u306f\u3001\u5065\u5e38\u8005\u306e\u30e1\u30e9\u30cb\u30f3\u7d30\u80de\u306b\u6bd4\u3079\u308b\u3068\u3001GalNAc\u3068NeuAc\uff08\u30b7\u30a2\u30eb\u9178\uff09\uff08\u305d\u308c\u305e\u308c\u3001WFA\u3068MAA\u306b\u3088\u3063\u3066\u691c\u51fa\u3055\u308c\u308b\uff09\u304c\u9ad8\u767a\u73fe\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3059\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/03\/melanoma_glycosylation.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/03\/melanoma_glycosylation-300x196.png\" alt=\"\" width=\"300\" height=\"196\" class=\"alignnone size-medium wp-image-12451\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/03\/melanoma_glycosylation-300x196.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/03\/melanoma_glycosylation-600x392.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/03\/melanoma_glycosylation-230x150.png 230w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/03\/melanoma_glycosylation-350x229.png 350w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/03\/melanoma_glycosylation-480x314.png 480w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/03\/melanoma_glycosylation.png 673w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>\u5168\u751f\u5b58\u671f\u9593\uff08OS\u4e2d\u592e\u5024\uff09\u307e\u305f\u306f\u7121\u5897\u60aa\u751f\u5b58\u671f\u9593\uff08PFS\u4e2d\u592e\u5024\uff09\u306e\u826f\u3057\u60aa\u3057\u306b\u57fa\u3065\u3044\u3066\u3001\u30e1\u30e9\u30ce\u30fc\u30de\u60a3\u8005\u306e\u7cd6\u9396\u4fee\u98fe\u306e\u5168\u4f53\u7684\u306a\u7279\u5fb4\u3092\u541f\u5473\u3059\u308b\u3068\u3001\u81e8\u5e8a\u8ee2\u5e30\u304c\u60aa\u3044\u60a3\u8005\u306e\u30e1\u30e9\u30ce\u30fc\u30de\u306b\u304a\u3044\u3066\u306f\u3001TF-\u6297\u539f\u3001GlcNAc\u3001Fuc\u3001\u305d\u3057\u3066NeuAc\u3089\u304c\u9ad8\u767a\u73fe\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\uff08\u305e\u308c\u305e\u308c\u306e\u7cd6\u9396\u4fee\u98fe\u6b8b\u57fa\u306f\u3001ACA\u3001WGA\u3001RPL-\u03b1Man\u3001UEA-I\u3001MAA\u3001\u304a\u3088\u3073 SNA 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\u306b\u3088\u3063\u3066\u691c\u51fa\u3055\u308c\u308b\uff09\u306f\u3088\u308a\u826f\u3044PFS\u3068\u76f8\u95a2\u3057\u3001\u9ad8\u30ec\u30d9\u30eb\u306eNeuAc\u304a\u3088\u3073Fuc\uff08\u305d\u308c\u305e\u308c SNA\u3001MAA\u3001\u307e\u305f\u306f UEA-I \u306b\u3088\u3063\u3066\u691c\u51fa\u3055\u308c\u308b\uff09\u3067\u306f\u81e8\u5e8a\u8ee2\u5e30\u304c\u826f\u304f\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u3092\u5f37\u8abf\u3057\u3066\u304a\u304f\u3079\u304d\u304b\u3082\u77e5\u308c\u307e\u305b\u3093\u3002<\/p>\n<p>\u8208\u5473\u6df1\u3044\u3053\u3068\u306b\u3001\u30e1\u30e9\u30ce\u30fc\u30de\u4e0a\u306eMan\/Glc\u304a\u3088\u3073GlcNAc\u306e\u30ec\u30d9\u30eb\u3068\u3001\u816b\u760d\u6d78\u6f64\u6027\u306ecDC1\u306e\u5272\u5408\u3068\u306e\u9593\u306b\u6b63\u306e\u76f8\u95a2\u304c\u3042\u308a\u307e\u3057\u305f\u3002Man\/Glc\u306f\u826f\u597d\u306a\u81e8\u5e8a\u8ee2\u5e30\u3068\u95a2\u9023\u3057\u3066\u304a\u308a\u3001GlcNAc\u306fcDC1\u306e\u6a5f\u80fd\u3092\u9ad8\u3081\u308b\u5019\u88dc\u3067\u3057\u305f\u3002\u30e1\u30e9\u30ce\u30fc\u30de\u4e0a\u306eFuc\u306e\u30ec\u30d9\u30eb\u306f\u3001T-\u7d30\u80de\u306b\u3088\u308b\u6d78\u6f64\u3068\u8ca0\u306e\u76f8\u95a2\u304c\u3042\u308a\u3001\u4e88\u5f8c\u4e0d\u826f\u3068\u3082\u95a2\u9023\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u30e1\u30e9\u30ce\u30fc\u30de\u60a3\u8005\u306e\u816b\u760d\u7d30\u80de\u4e0a\u306eTF-\u6297\u539f\u306e\u30ec\u30d9\u30eb\u306f\u3001CD8+ 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class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-12447","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"Institute for Advanced Biosciences, Universit\u00e9 Grenoble\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"Mx\"\/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.emukk.com\/WP\/%e3%83%a1%e3%83%a9%e3%83%8e%e3%83%bc%e3%83%9e%e3%81%ae%e7%89%b9%e7%95%b0%e7%9a%84%e3%81%aa%e7%b3%96%e9%8e%96%e4%bf%ae%e9%a3%be%e5%a4%89%e5%8c%96%e3%81%8c%e6%a8%b9%e7%8a%b6%e7%b4%b0%e8%83%9e%e3%81%ae\/\" \/>\n\t<meta name=\"generator\" content=\"All in One 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