{"id":12350,"date":"2023-02-25T08:19:38","date_gmt":"2023-02-24T23:19:38","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=12350"},"modified":"2023-02-25T08:33:54","modified_gmt":"2023-02-24T23:33:54","slug":"glycan-binding-specificity-of-wfa-is-quite-similar-to-that-of-vva","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/en\/glycan-binding-specificity-of-wfa-is-quite-similar-to-that-of-vva\/","title":{"rendered":"Glycan binding specificity of WFA is quite similar to that of VVA"},"content":{"rendered":"<p>A group from Department of Chemistry and Center for Diagnostics &amp; Therapeutics, Georgia State University, Atlanta, GA, USA, etc. has reported about chemoenzymatically synthesized O-glycan arrays.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9931048\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9931048\/<\/a><\/p>\n<p>WFA is know to be a quite useful lectin in diagnosis.<br \/>\nAccording to this study, WFA and VVA strongly bind all structures with a terminal unmodified GalNAc residue, including Tn-antigen, core 5, sialyl-core 5, and core 7, as shown below.<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/02\/WFAVVA.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-12346\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/02\/WFAVVA-300x127.png\" alt=\"\" width=\"300\" height=\"127\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/02\/WFAVVA-300x127.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/02\/WFAVVA-600x253.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/02\/WFAVVA-768x324.png 768w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/02\/WFAVVA-230x97.png 230w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/02\/WFAVVA-350x148.png 350w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/02\/WFAVVA-480x202.png 480w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/02\/WFAVVA.png 830w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a> No.24 is Tn-antigen<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A group from Department of Chemistry and Center for Diagnostics &amp; Therapeutics, Georgia State University, <\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/en\/glycan-binding-specificity-of-wfa-is-quite-similar-to-that-of-vva\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-12350","post","type-post","status-publish","format-standard","hentry","category-technology-en"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/12350","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=12350"}],"version-history":[{"count":3,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/12350\/revisions"}],"predecessor-version":[{"id":12355,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/12350\/revisions\/12355"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=12350"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=12350"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=12350"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}