{"id":12040,"date":"2023-01-05T13:54:09","date_gmt":"2023-01-05T04:54:09","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=12040"},"modified":"2023-01-05T13:56:26","modified_gmt":"2023-01-05T04:56:26","slug":"changes-in-glycan-patterns-in-the-medial-prefrontal-cortex-of-autism-spectrum-disorders-asd-rats","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/en\/changes-in-glycan-patterns-in-the-medial-prefrontal-cortex-of-autism-spectrum-disorders-asd-rats\/","title":{"rendered":"Changes in glycan patterns in the medial prefrontal cortex of autism spectrum disorders (ASD) rats"},"content":{"rendered":"<p>A group from College of Life Sciences, Shaanxi Normal University, Xi\u2019an, Shaanxi, China, etc, has reported about changes in glycan patterns and glycan-related genes in the medial prefrontal cortex of autism spectrum disorders (ASD) rats.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9772556\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9772556\/<\/a><\/p>\n<p>With using lectin microarrays, the following changes in glycosylation were found in ASD rats.<br \/>\n(1) Branched high-mannose (recognized by ConA) was upregurated in ASD rats,<br \/>\n(2) complex-type antennary agalacto N-glycan (recognized by GSL-II and PHA-E) was up-regulated in ASD rats, and<br \/>\n(3) Sia\u03b12-3 Gal\/GalNAc (recognized by WGA and MAL-I) and terminal GalNAc structure (recognized by BPL and VVA) were down-regulated in ASD rats.<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/01\/ASD-rats\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-12037\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/01\/ASD-rats-300x137.png\" alt=\"\" width=\"300\" height=\"137\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/01\/ASD-rats-300x137.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/01\/ASD-rats-600x274.png 600w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/01\/ASD-rats-768x351.png 768w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/01\/ASD-rats-1000x457.png 1000w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/01\/ASD-rats-230x105.png 230w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/01\/ASD-rats-350x160.png 350w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/01\/ASD-rats-480x219.png 480w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2023\/01\/ASD-rats.png 1007w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A group from College of Life Sciences, Shaanxi Normal University, Xi\u2019an, Shaanxi, China, etc, has reported abo<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/en\/changes-in-glycan-patterns-in-the-medial-prefrontal-cortex-of-autism-spectrum-disorders-asd-rats\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70],"tags":[],"class_list":["post-12040","post","type-post","status-publish","format-standard","hentry","category-nature-en"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/12040","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=12040"}],"version-history":[{"count":1,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/12040\/revisions"}],"predecessor-version":[{"id":12041,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/12040\/revisions\/12041"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=12040"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=12040"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=12040"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}