{"id":1153,"date":"2020-11-06T13:14:53","date_gmt":"2020-11-06T04:14:53","guid":{"rendered":"http:\/\/www.emukk.com\/WP\/?p=1153"},"modified":"2021-07-21T23:57:59","modified_gmt":"2021-07-21T14:57:59","slug":"tnf-%ce%b1%e3%81%a8ifn-%ce%b3%e3%81%ae%e5%8d%94%e5%90%8c%e5%8a%b9%e6%9e%9c%e3%81%8c%e3%80%81%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88covid-19%ef%bc%89","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/tnf-%ce%b1%e3%81%a8ifn-%ce%b3%e3%81%ae%e5%8d%94%e5%90%8c%e5%8a%b9%e6%9e%9c%e3%81%8c%e3%80%81%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88covid-19%ef%bc%89\/","title":{"rendered":"TNF-\u03b1\u3068IFN-\u03b3\u306e\u5354\u540c\u52b9\u679c\u304c\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\uff08COVID-19\uff09\u306e\u91cd\u75c7\u5316\u306e\u6838\u5fc3\u306b\u3042\u308b\u3088\u3046\u3060"},"content":{"rendered":"<p>\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u3067COVID-19\u3092\u767a\u75c7\u3057\u91cd\u75c7\u5316\u3057\u305f\u5834\u5408\u306b\u306f\u3001IL-6, IL-18, IFN-\u03b3, IL-15, TNF-\u03b1, IL-1\u03b1, IL-1\u03b2, IL-2\u3068\u3044\u3063\u305f\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u304c\u9ad8\u767a\u73fe\u3057\u3001\u3044\u308f\u3086\u308b\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u30b9\u30c8\u30fc\u30e0\u72b6\u614b\u306b\u9665\u308a\u307e\u3059\u3002COVID-19\u306e\u6025\u6027\u547c\u5438\u7aae\u8feb\u75c7\u5019\u7fa4\uff08ARDS)\u304c\u3001\u3053\u306e\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u30b9\u30c8\u30fc\u30e0\u3068\u76f4\u63a5\u7684\u306b\u76f8\u95a2\u3057\u3066\u3044\u308b\u3053\u3068\u306f\u5e83\u304f\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u3053\u306e\u3088\u3046\u306a\u591a\u69d8\u306a\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u767a\u73fe\u306b\u304a\u3044\u3066\u3001\u7279\u306bTNF-\u03b1, IFN-\u03b3\u306e\u5354\u540c\u52b9\u679c\u304c\u91cd\u75c7\u5316\u306e\u539f\u56e0\u306b\u306a\u3063\u3066\u3044\u308b\u3089\u3057\u3044\u3068\u3044\u3046\u3053\u3068\u304c\u4e0b\u8a18\u306e\u30b0\u30eb\u30fc\u30d7\u304b\u3089\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7605562\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7605562\/<\/a><\/p>\n<p>TNF-\u03b1, IFN-\u03b3\u306e\u5354\u540c\u52b9\u679c\u304c\u3001COVID-19\u306e\u75c7\u72b6\u3092\u6a21\u5023\u3059\u308b\u3068\u3044\u3046\u3053\u3068\u306e\u30de\u30a6\u30b9\u3092\u7528\u3044\u305fin vivo\u691c\u8a3c\u4f8b\u304c\u4e0b\u8a18\u3067\u3059\u3002<br \/>\n<a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2020\/11\/TNF-IFN_SARS-CoV-2.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-thumbnail wp-image-1156\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2020\/11\/TNF-IFN_SARS-CoV-2-150x150.png\" alt=\"\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2020\/11\/TNF-IFN_SARS-CoV-2-150x150.png 150w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2020\/11\/TNF-IFN_SARS-CoV-2-300x300.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2020\/11\/TNF-IFN_SARS-CoV-2-100x100.png 100w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>\u307e\u305f\u3001SARS-CoV-2\u3092\u611f\u67d3\u3055\u305b\u305fhACE2\u30c8\u30e9\u30f3\u30b9\u30b8\u30a7\u30cb\u30c3\u30af\u30de\u30a6\u30b9\u306bTNF-\u03b1, IFN-\u03b3\u306e\u4e2d\u548c\u6297\u4f53\u3092\u30a2\u30d7\u30e9\u30a4\u3059\u308b\u3053\u3068\u3067\u3001\u751f\u5b58\u7387\u304c\u5927\u304d\u304f\u30a2\u30c3\u30d7\u3059\u308b\u3053\u3068\u3082in vivo\u3067\u691c\u8a3c\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2020\/11\/TNF-IFN-Ab_SARS-CoV-2.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-thumbnail wp-image-1157\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2020\/11\/TNF-IFN-Ab_SARS-CoV-2-150x150.png\" alt=\"\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2020\/11\/TNF-IFN-Ab_SARS-CoV-2-150x150.png 150w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2020\/11\/TNF-IFN-Ab_SARS-CoV-2-300x300.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2020\/11\/TNF-IFN-Ab_SARS-CoV-2-100x100.png 100w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>\u5373\u3061\u3001TNF-\u03b1, IFN-\u03b3\u3092\u542b\u3081\u305d\u306e\u4e0b\u6d41\u306b\u3042\u308b\u30b7\u30b0\u30ca\u30eb\u30d1\u30b9\u306b\u5bfe\u3059\u308b\u7684\u3092\u7a81\u3044\u305f\u963b\u5bb3\u5264\u304cCOVID-19\u306e\u91cd\u75c7\u5316\u6cbb\u7642\u306b\u3064\u306a\u304c\u308a\u305d\u3046\u3067\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u3067COVID-19\u3092\u767a\u75c7\u3057\u91cd\u75c7\u5316\u3057\u305f\u5834\u5408\u306b\u306f\u3001IL-6, IL-18, IFN-\u03b3, IL-15, TNF-\u03b1, IL-1\u03b1, IL-1\u03b2, IL-2\u3068\u3044\u3063\u305f\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u304c\u9ad8\u767a\u73fe\u3057\u3001\u3044\u308f\u3086\u308b\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/tnf-%ce%b1%e3%81%a8ifn-%ce%b3%e3%81%ae%e5%8d%94%e5%90%8c%e5%8a%b9%e6%9e%9c%e3%81%8c%e3%80%81%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%ef%bc%88covid-19%ef%bc%89\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-1153","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/1153","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=1153"}],"version-history":[{"count":9,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/1153\/revisions"}],"predecessor-version":[{"id":5182,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/1153\/revisions\/5182"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=1153"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=1153"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=1153"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}