{"id":11017,"date":"2022-11-22T07:59:57","date_gmt":"2022-11-21T22:59:57","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=11017"},"modified":"2022-11-22T08:11:09","modified_gmt":"2022-11-21T23:11:09","slug":"%e3%83%92%e3%83%88%e3%81%aedectin-1%e6%ac%a0%e4%b9%8f%e7%97%87%e3%81%8c%e9%bb%92%e8%89%b2%e8%8f%8c%e7%b3%b8%e7%97%87%ef%bc%88phaeohyphomycosis%ef%bc%89%e3%81%ab%e4%b8%8e%e3%81%88%e3%82%8b%e6%b7%b1","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/%e3%83%92%e3%83%88%e3%81%aedectin-1%e6%ac%a0%e4%b9%8f%e7%97%87%e3%81%8c%e9%bb%92%e8%89%b2%e8%8f%8c%e7%b3%b8%e7%97%87%ef%bc%88phaeohyphomycosis%ef%bc%89%e3%81%ab%e4%b8%8e%e3%81%88%e3%82%8b%e6%b7%b1\/","title":{"rendered":"\u30d2\u30c8\u306eDectin-1\u6b20\u4e4f\u75c7\u304c\u9ed2\u8272\u83cc\u7cf8\u75c7\uff08phaeohyphomycosis\uff09\u306b\u4e0e\u3048\u308b\u6df1\u523b\u306a\u5f71\u97ff"},"content":{"rendered":"

Fungal Pathogenesis Section and Immunopathogenesis Section, Laboratory of Clinical Immunology and Microbiology (LCIM), National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, USA\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30d2\u30c8\u306eDectin-1\u6b20\u4e4f\u75c7\u304c\u9ed2\u8272\u83cc\u7cf8\u75c7\uff08phaeohyphomycosis\uff09\u306b\u5bfe\u3059\u308b\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u514d\u75ab\u9632\u5fa1\u3092\u5f31\u3081\u308b\u3068\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002
\nhttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9663159\/<\/a><\/p>\n

\u9ed2\u8272\u83cc\u7cf8\u75c7\u306f\u3001\u30e1\u30e9\u30cb\u30f3\u7523\u751f\u3068\u7cf8\u72b6\u5897\u6b96\u3092\u7279\u5fb4\u3068\u3059\u308b\u76ae\u819a\u771f\u83cc\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u4fb5\u8972\u6027\u771f\u83cc\u611f\u67d3\u75c7\u3067\u3059\u3002\u9ed2\u8272\u83cc\u7cf8\u75c7\u306f\u3001\u901a\u5e38\u3001\u5916\u50b7\u304b\u3089\u611f\u67d3\u3057\u3066\u76ae\u4e0b\u7d44\u7e54\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3057\u3001\u6297\u771f\u83cc\u7642\u6cd5\u304a\u3088\u3073\uff0f\u307e\u305f\u306f\u5916\u79d1\u7684\u5207\u9664\u3067\u6cbb\u7642\u53ef\u80fd\u3067\u3059\u3002<\/p>\n

\u672c\u7814\u7a76\u3067\u306f\u3001CARD9\u6b20\u640d\u75c7\u3067\u751f\u547d\u3092\u8105\u304b\u3059\u611f\u67d3\u75c7\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u308b\u690d\u7269\u306e\u9ed2\u8272\u771f\u83cc\u3067\u3042\u308bCorynespora cassiicola\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u91cd\u5ea6\u306e\u9ed2\u8272\u83cc\u7cf8\u75c7\u306e\u60a3\u8005\u306b\u7126\u70b9\u304c\u5f53\u3066\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u60a3\u8005\u306f\u3001CARD9 \u5171\u5f79\u53d7\u5bb9\u4f53\u3067\u3042\u308b Dectin-1 \u3092\u30b3\u30fc\u30c9\u3059\u308b CLEC7A \u306b\u4e21\u30a2\u30ec\u30eb\u5909\u7570\u304c\u3042\u308a\u307e\u3057\u305f\u3002 Dectin-1 \u306f\u3001\u30d2\u30c8\u514d\u75ab\u7d30\u80de\u306b\u3088\u308b\u3053\u306e\u771f\u83cc\u306b\u5bfe\u3059\u308b IL-1\u03b2 \u304a\u3088\u3073 TNF-\u03b1 \u306e\u7523\u751f\u306b\u91cd\u8981\u3067\u3042\u308a\u3001\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306b\u3088\u308b\u771f\u83cc\u306e\u6bba\u50b7\u3092\u4fc3\u9032\u3057\u307e\u3059\u3002 CARD9\u3068\u306f\u3001C-\u578b\u30ec\u30af\u30c1\u30f3\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3068\u6297\u771f\u83cc\u514d\u75ab\u306b\u95a2\u4e0e\u3059\u308b\u9aa8\u9ac4\u7d30\u80de\u306e\u514d\u75ab\u30a2\u30c0\u30d7\u30bf\u30fc\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u3053\u306e\u60a3\u8005\u3068\u306f\u8840\u7e01\u95a2\u4fc2\u306e\u306a\u3044\u91cd\u5ea6\u306e\u9ed2\u8272\u83cc\u7cf8\u75c7\u60a3\u8005 17 \u4eba\u3082\u8a55\u4fa1\u3055\u308c\u300117 \u4eba\u4e2d 12 \u4eba\u306b\u6709\u5bb3\u306a CLEC7A \u5909\u7570\u304c\u5b58\u5728\u3057\u3001Dectin-1 \u7d30\u80de\u5916\u3001\u03b2-\u30b0\u30eb\u30ab\u30f3\u7d50\u5408\u3001C-\u672b\u7aef\u30c9\u30e1\u30a4\u30f3\u3089\u306e\u5909\u5316\u3068\u95a2\u9023\u3057\u3066\u3001Decin-1\u2013\u4f9d\u5b58\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u7523\u751f\u969c\u5bb3\u3092\u5f15\u304d\u304a\u3053\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n

\"\"<\/a><\/p>\n

Dectin-1\u6b20\u640d\u60a3\u8005\u304a\u3088\u3073CARD9\u6b20\u640d\u60a3\u8005\u306e\u3053\u306e\u771f\u83cc\u306b\u5bfe\u3059\u308b\u708e\u75c7\u8a98\u767a\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u5fdc\u7b54\u306e\u9055\u3044\u3092\u793a\u3059<\/p>\n","protected":false},"excerpt":{"rendered":"

Fungal Pathogenesis Section and Immunopathogenesis Section, Laboratory of Clinical Immunology and Microbiology<\/p><\/div>\n

\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[642],"tags":[],"class_list":["post-11017","post","type-post","status-publish","format-standard","hentry","category-nature-ja"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/11017","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=11017"}],"version-history":[{"count":8,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/11017\/revisions"}],"predecessor-version":[{"id":11158,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/11017\/revisions\/11158"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=11017"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=11017"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=11017"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}