{"id":10828,"date":"2022-11-08T16:20:37","date_gmt":"2022-11-08T07:20:37","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=10828"},"modified":"2022-11-08T16:26:01","modified_gmt":"2022-11-08T07:26:01","slug":"characteristic-glycan-modification-of-sars-cov-2-omicron-variant-comparing-with-other-variants","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/en\/characteristic-glycan-modification-of-sars-cov-2-omicron-variant-comparing-with-other-variants\/","title":{"rendered":"Characteristic glycan modification of SARS-CoV-2 Omicron variant comparing with other variants"},"content":{"rendered":"<p>A group from Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China, etc. has reported about characteristic glycan modification of SARS-CoV-2 Omicron variant comparing with other variants.<br \/>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36318020\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/36318020\/<\/a><\/p>\n<p>I thought I would stop blogging about SARS-CoV-2, but I would like to briefly introduce this paper it as a topic related to comparative glycan profiling analysis using lectin microarrays.<\/p>\n<p>From the comparative glycan profiling analysis, it was found that SARS-CoV-2 Omicron showed higher levels of terminal fucose (UEA-I), and also showed higher level of sialylated (MAL-II, MAA, ASNA-I) and galactosylated glycans (CSA, WFA, SBA, VVL) than other variants (Alpha, Beta, and Delta).<\/p>\n<p>SARS-CoV-2 Omicron was more susceptible to neutralization antibodies after neuraminidase or galactosidase treatment. This means that the higher expression of both Sia- and Gal-containing glycans on Omicron potentially enhance its shielding effect against neutralization.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A group from Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sc<\/p><\/div>\n<div class=\"blog-btn\"><a href=\"https:\/\/www.emukk.com\/WP\/en\/characteristic-glycan-modification-of-sars-cov-2-omicron-variant-comparing-with-other-variants\/\" class=\"home-blog-btn\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70],"tags":[],"class_list":["post-10828","post","type-post","status-publish","format-standard","hentry","category-nature-en"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/10828","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/comments?post=10828"}],"version-history":[{"count":1,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/10828\/revisions"}],"predecessor-version":[{"id":10829,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/posts\/10828\/revisions\/10829"}],"wp:attachment":[{"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/media?parent=10828"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/categories?post=10828"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emukk.com\/WP\/wp-json\/wp\/v2\/tags?post=10828"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}