{"id":10522,"date":"2022-10-17T11:02:28","date_gmt":"2022-10-17T02:02:28","guid":{"rendered":"https:\/\/www.emukk.com\/WP\/?p=10522"},"modified":"2022-10-17T11:02:28","modified_gmt":"2022-10-17T02:02:28","slug":"slex%e3%81%ab%e7%b5%90%e5%90%88%e7%89%b9%e7%95%b0%e6%80%a7%e3%82%92%e6%8c%81%e3%81%a4e-%e3%82%bb%e3%83%ac%e3%82%af%e3%83%81%e3%83%b3%e3%82%92-6%e2%80%b2-sulfo-slex%e3%81%ab%e5%af%be%e3%81%99","status":"publish","type":"post","link":"https:\/\/www.emukk.com\/WP\/slex%e3%81%ab%e7%b5%90%e5%90%88%e7%89%b9%e7%95%b0%e6%80%a7%e3%82%92%e6%8c%81%e3%81%a4e-%e3%82%bb%e3%83%ac%e3%82%af%e3%83%81%e3%83%b3%e3%82%92-6%e2%80%b2-sulfo-slex%e3%81%ab%e5%af%be%e3%81%99\/","title":{"rendered":"(sLex)\u306b\u7d50\u5408\u7279\u7570\u6027\u3092\u6301\u3064E-\u30bb\u30ec\u30af\u30c1\u30f3\u3092 (6\u2032-sulfo-sLex)\u306b\u5bfe\u3059\u308b\u7d50\u5408\u7279\u7570\u6027\u306b\u6539\u5909\u3059\u308b"},"content":{"rendered":"<p>Complex Carbohydrate Research Center, University of Georgia, Athens, GA 30602\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001E-\u30bb\u30ec\u30af\u30c1\u30f3\u306e\u7cd6\u9396\u7d50\u5408\u7279\u7570\u6027\u3092\u4e8c\u30b1\u6240\u306b\u5909\u7570\u3092\u5165\u308c\u308b\u3053\u3068\u3067 sLex \u304b\u3089 6\u2032-sulfo-sialyl Lewis X \u306b\u5909\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3068\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9564326\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9564326\/<\/a><\/p>\n<p>\u30ec\u30af\u30c1\u30f3\u306f\u7cd6\u9396\u306e\u691c\u51fa\u306b\u3088\u304f\u4f7f\u7528\u3055\u308c\u307e\u3059\u304c\u3001\u786b\u9178\u5316\u7cd6\u9396\u3078\u306e\u9069\u7528\u306f\u3001\u786b\u9178\u5316\u7cd6\u9396\u306e\u8a8d\u8b58\u30ec\u30af\u30c1\u30f3\u304c\u6b86\u3069\u306a\u3044\u3053\u3068\u3068\u3001\u305d\u306e\u30d6\u30ed\u30fc\u30c9\u306a\u7279\u7570\u6027\u306e\u305f\u3081\u306b\u975e\u5e38\u306b\u56f0\u96e3\u3067\u3059\u3002<\/p>\n<p>\u672c\u7814\u7a76\u3067\u306f\u3001E-\u30bb\u30ec\u30af\u30c1\u30f3\u306b\u7740\u76ee\u3057\u30016&#8242;-sulfate\u3068E-\u30bb\u30ec\u30af\u30c1\u30f3\u306eE92\u304a\u3088\u3073E107\u3068\u306e\u9593\u306e\u4e0d\u5b89\u5b9a\u5316\u306a\u7acb\u4f53\u7684\u304a\u3088\u3073\u9759\u96fb\u7684\u76f8\u4e92\u4f5c\u7528\u3092E92A\/E107A\u3068\u3044\u3046\u4e8c\u500b\u306e\u5909\u7570\u3092\u633f\u5165\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u9664\u53bb\u3057\u30016\u2032-sulfo-sLex\u306b\u5bfe\u3059\u308b\u65b0\u305f\u306a\u7d50\u5408\u7279\u7570\u6027\u3092\u6301\u3064\u3088\u3046\u306b\u6539\u5909\u3057\u3066\u3044\u307e\u3059\u3002\u826f\u304f\u77e5\u3089\u308c\u3066\u3044\u308b\u3088\u3046\u306b\u3001E-\u30bb\u30ec\u30af\u30c1\u30f3\u81ea\u4f53\u306f\u3001\u975e\u786b\u9178\u5316\u30ea\u30ac\u30f3\u30c9 sLex \u306b\u7279\u7570\u7684\u306a\u7d50\u5408\u3092\u793a\u3057\u307e\u3059\u3002<br \/>\n\u3053\u306e\u65b0\u3057\u3044\u7cd6\u9396\u7d50\u5408\u7279\u7570\u6027\u306f\u30016&#8242;-sulfo-sLex \u304c\u512a\u5148\u30ea\u30ac\u30f3\u30c9\u3067\u3042\u308b Siglec-8 \u306e\u7279\u7570\u6027\u3092\u826f\u304f\u6a21\u5023\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><a href=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/10\/E-selectin-with-E92AE107A.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-10523\" src=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/10\/E-selectin-with-E92AE107A-300x158.png\" alt=\"\" width=\"300\" height=\"158\" srcset=\"https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/10\/E-selectin-with-E92AE107A-300x158.png 300w, https:\/\/www.emukk.com\/WP\/wp-content\/uploads\/2022\/10\/E-selectin-with-E92AE107A-600x315.png 600w, 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